FLT3/ITD associated with an immature immunophenotype in PML-RARα leukemia
Acute promyelocytic leukemia (APL) is characterized by the specific PML-RARα fusion gene resulting from translocation t(15;17) (q22;q12). Internal tandem duplication (ITD) of the FLT3 gene has been observed in approximately 35% of APLs, and large-scale studies have identified the presence of ITD as...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
PAGEPress Publications
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555210/ |