HIV-1 Fusion Is Blocked through Binding of GB Virus C E2D Peptides to the HIV-1 gp41 Disulfide Loop

HIV-1 Fusion Is Blocked through Binding of GB Virus C E2D Peptides to the HIV-1 gp41 Disulfide Loop

A strategy for antiviral drug discovery is the elucidation and imitation of viral interference mechanisms. HIV-1 patients benefit from a coinfection with GB Virus C (GBV-C), since HIV-positive individuals with long-term GBV-C viraemia show better survival rates than HIV-1 patients without persisting...

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Bibliographic Details
Main Authors: Eissmann, Kristin, Mueller, Sebastian, Sticht, Heinrich, Jung, Susan, Zou, Peng, Jiang, Shibo, Gross, Andrea, Eichler, Jutta, Fleckenstein, Bernhard, Reil, Heide
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551756/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551756/

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