A cell-based screening system for influenza A viral RNA transcription/replication inhibitors

A cell-based screening system for influenza A viral RNA transcription/replication inhibitors

Although two classes of antivirals, NA inhibitors and M2 ion channel blockers, are licensed for influenza treatment, dual resistant mutants, including highly pathogenic H5N1 viruses, have appeared. Alternative treatment options are, therefore, needed. Influenza A viral RNA (vRNA) transcription/repli...

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Bibliographic Details
Main Authors: Ozawa, Makoto, Shimojima, Masayuki, Goto, Hideo, Watanabe, Shinji, Hatta, Yasuko, Kiso, Maki, Furuta, Yousuke, Horimoto, Taisuke, Peters, Noel R., Hoffmann, F. Michael, Kawaoka, Yoshihiro
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551287/

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