An orally available, small-molecule interferon inhibits viral replication

Most acute hepatitis C virus (HCV) infections become chronic and some progress to liver cirrhosis or hepatocellular carcinoma. Standard therapy involves an interferon (IFN)-α-based regimen, and efficacy of therapy has been significantly improved by the development of protease inhibitors. However, se...

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Bibliographic Details
Main Authors: Konishi, Hideyuki, Okamoto, Koichi, Ohmori, Yusuke, Yoshino, Hitoshi, Ohmori, Hiroshi, Ashihara, Motooki, Hirata, Yuichi, Ohta, Atsunori, Sakamoto, Hiroshi, Hada, Natsuko, Katsume, Asao, Kohara, Michinori, Morikawa, Kazumi, Tsukuda, Takuo, Shimma, Nobuo, Foster, Graham R., Alazawi, William, Aoki, Yuko, Arisawa, Mikio, Sudoh, Masayuki
Format: Online
Language:English
Published: Nature Publishing Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277087/