How helminths use excretory secretory fractions to modulate dendritic cells

It is well known that helminth parasites have immunomodulatory effects on their hosts. They characteristically cause a skew toward TH2 immunity, stimulate Treg cells while simultaneously inhibiting TH1 and TH17 responses. Additionally, they induce eosinophilia and extensive IgE release. The exact me...

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Bibliographic Details
Main Authors: White, Rhiannon R., Artavanis-Tsakonas, Katerina
Format: Online
Language:English
Published: Landes Bioscience 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545949/