Heterogeneity of breast cancer stem cells as evidenced with Notch-dependent and Notch-independent populations
Studies have suggested the potential importance of Notch signaling to the cancer stem cell population in some tumors, but it is not known whether all cells in the cancer stem cell fraction require Notch activity. To address this issue, we blocked Notch activity in MCF-7 cells by expressing a dominan...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Blackwell Publishing Ltd
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544441/ |