Phosphorylation-dependent regulation of Notch1 signaling: the fulcrum of Notch1 signaling

Notch signaling plays a pivotal role in cell fate determination, cellular development, cellular self-renewal, tumor progression, and has been linked to developmental disorders and carcinogenesis. Notch1 is activated through interactions with the ligands of neighboring cells, and acts as a transcript...

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Bibliographic Details
Main Authors: Lee, Hye-Jin, Kim, Mi-Yeon, Park, Hee-Sae
Format: Online
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576950/