Reductionism at the vertebrate kinetochore
The kinetochore forms the site of attachment for mitotic spindle microtubules driving chromosome segregation. The interdependent protein interactions in this large structure have made it difficult to dissect the function of its components. In this issue, Hori et al. (2013. J. Cell Biol. http://dx.do...
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The Rockefeller University Press
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542803/ |
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pubmed-35428032013-07-07 Reductionism at the vertebrate kinetochore Stankovic, Ana Jansen, Lars E.T. Reviews The kinetochore forms the site of attachment for mitotic spindle microtubules driving chromosome segregation. The interdependent protein interactions in this large structure have made it difficult to dissect the function of its components. In this issue, Hori et al. (2013. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201210106) present a novel and powerful methodology to address the sufficiency of individual proteins for the creation of a functional de novo centromere. The Rockefeller University Press 2013-01-07 /pmc/articles/PMC3542803/ /pubmed/23277428 http://dx.doi.org/10.1083/jcb.201212005 Text en © 2013 Stankovic and Jansen This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/). |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Stankovic, Ana Jansen, Lars E.T. |
| spellingShingle |
Stankovic, Ana Jansen, Lars E.T. Reductionism at the vertebrate kinetochore |
| author_facet |
Stankovic, Ana Jansen, Lars E.T. |
| author_sort |
Stankovic, Ana |
| title |
Reductionism at the vertebrate kinetochore |
| title_short |
Reductionism at the vertebrate kinetochore |
| title_full |
Reductionism at the vertebrate kinetochore |
| title_fullStr |
Reductionism at the vertebrate kinetochore |
| title_full_unstemmed |
Reductionism at the vertebrate kinetochore |
| title_sort |
reductionism at the vertebrate kinetochore |
| description |
The kinetochore forms the site of attachment for mitotic spindle microtubules
driving chromosome segregation. The interdependent protein interactions in this
large structure have made it difficult to dissect the function of its
components. In this issue, Hori et al. (2013. J. Cell Biol.
http://dx.doi.org/10.1083/jcb.201210106) present a novel and powerful
methodology to address the sufficiency of individual proteins for the creation
of a functional de novo centromere. |
| publisher |
The Rockefeller University Press |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542803/ |
| _version_ |
1611946308215504896 |