The VMP1-Beclin 1 interaction regulates autophagy induction

The Vacuole Membrane Protein 1 -VMP1- is a pancreatitis-associated transmembrane protein whose expression triggers autophagy in several human diseases. In the current study, we unveil the mechanism through which this protein induces autophagosome formation in mammalian cells. We show that VMP1 autop...

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Bibliographic Details
Main Authors: Molejon, Maria I., Ropolo, Alejandro, Re, Andrea Lo, Boggio, Veronica, Vaccaro, Maria I.
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542764/