Fingerloop activates cargo delivery and unloading during cotranslational protein targeting
During protein targeting by the signal recognition particle (SRP), signals from cargo binding in the SRP's M domain must be communicated to its GTPase domain to initiate the membrane delivery of cargo. In this study, a conserved fingerloop lining the signal sequence–binding groove of SRP is sho...
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Bibliographic Details
| Main Authors: |
Ariosa, Aileen R.,
Duncan, Stacy S.,
Saraogi, Ishu,
Lu, Xiaodong,
Brown, April,
Phillips, Gregory J.,
Shan, Shu-Ou |
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| Format: | Online
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| Language: | English |
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| Published: |
The American Society for Cell Biology
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541965/
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