Fingerloop activates cargo delivery and unloading during cotranslational protein targeting

Fingerloop activates cargo delivery and unloading during cotranslational protein targeting

During protein targeting by the signal recognition particle (SRP), signals from cargo binding in the SRP's M domain must be communicated to its GTPase domain to initiate the membrane delivery of cargo. In this study, a conserved fingerloop lining the signal sequence–binding groove of SRP is sho...

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Bibliographic Details
Main Authors: Ariosa, Aileen R., Duncan, Stacy S., Saraogi, Ishu, Lu, Xiaodong, Brown, April, Phillips, Gregory J., Shan, Shu-Ou
Format: Online
Language:English
Published: The American Society for Cell Biology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541965/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541965/

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