MiR-145 reduces ADAM17 expression and inhibits in vitro migration and invasion of glioma cells
MicroRNAs are important regulators of gene expression and have been suggested to play a key role in tumorigenesis. In this study, we show that miR-145 is significantly downregulated in glioma cell lines compared to normal brain tissue and negatively regulates tumorigenesis. Restoration of miR-145 in...
Main Authors: | LU, YONG, CHOPP, MICHAEL, ZHENG, XUGUANG, KATAKOWSKI, MARK, BULLER, BENJAMIN, JIANG, FENG |
---|---|
Format: | Online |
Language: | English |
Published: |
D.A. Spandidos
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540808/ |
Similar Items
-
Overexpression of miR-145 in U87 cells reduces glioma cell malignant phenotype and promotes survival after in vivo implantation
by: LU, YONG, et al.
Published: (2014) -
Serial selection for invasiveness increases expression of miR-143/miR-145 in glioblastoma cell lines
by: Koo, Sunwoo, et al.
Published: (2012) -
miR-143 and miR-145 synergistically regulate ERBB3 to suppress cell proliferation and invasion in breast cancer
by: Yan, Xin, et al.
Published: (2014) -
Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer
by: Schee, Kristina, et al.
Published: (2012) -
MicroRNA Expression Profile Reveals miR-17-92 and miR-143-145 Cluster in Synchronous Colorectal Cancer
by: Meng, Wen-Jian, et al.
Published: (2015)