Comprehensive Analysis and Identification of the Human STIM1 Domains for Structural and Functional Studies

Comprehensive Analysis and Identification of the Human STIM1 Domains for Structural and Functional Studies

STIM1 is a Ca2+ sensor within the ER membrane known to activate the plasma membrane store-operated Ca2+ channel upon depletion of its target ion in the ER lumen. This activation is a crucial step to initiate the Ca2+ signaling cascades within various cell types. Human STIM1 is a 77.4 kDa protein con...

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Bibliographic Details
Main Authors: How, Jonathan, Zhang, Ai, Phillips, Margaret, Reynaud, Aline, Lu, Si Yan, Pan, Lucy Xin, Ho, Hai Ting, Yau, Yin Hoe, Guskov, Albert, Pervushin, Konstantin, Shochat, Susana Geifman, Eshaghi, Said
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540032/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540032/

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