Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc
Despite the high prevalence of intervertebral disc disease, little is known about changes in intervertebral disc cells and their regenerative potential with ageing and intervertebral disc degeneration. Here we identify populations of progenitor cells that are Tie2 positive (Tie2+) and disialoganglio...
Main Authors: | Sakai, Daisuke, Nakamura, Yoshihiko, Nakai, Tomoko, Mishima, Taishi, Kato, Shunichi, Grad, Sibylle, Alini, Mauro, Risbud, Makarand V., Chan, Danny, Cheah, Kathryn S.E., Yamamura, Ken-ichi, Masuda, Koichi, Okano, Hideyuki, Ando, Kiyoshi, Mochida, Joji |
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Format: | Online |
Language: | English |
Published: |
Nature Pub. Group
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535337/ |
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