Structural insight into the ligand-receptor interaction between glycyrrhetinic acid (GA) and the high-mobility group protein B1 (HMGB1)-DNA complex

Structural analysis of the high-mobility group protein B1 (HMGB1)-DNA complex and a docking simulation between glycyrrhetinic acid (GA) and the HMGB1-DNA complex were performed with a software package the Molecular Operating Environment (MOE). An HMGB1-DNA (PDB code: 2GZK) was selected for the 3D st...

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Bibliographic Details
Main Authors: Yamaguchi, Hideaki, Kidachi, Yumi, Kamiie, Katsuyoshi, Noshita, Toshiro, Umetsu, Hironori
Format: Online
Language:English
Published: Biomedical Informatics 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530883/