Mouse 11β-Hydroxysteroid Dehydrogenase Type 2 for Human Application: Homology Modeling, Structural Analysis and Ligand-Receptor Interaction

Mouse 11β-Hydroxysteroid Dehydrogenase Type 2 for Human Application: Homology Modeling, Structural Analysis and Ligand-Receptor Interaction

Mouse (m) 11β-hydroxysteroid dehydrogenase type 2 (11βHSD2) was homology-modeled, and its structure and ligand-receptor interaction were analyzed. The modeled m11βHSD2 showed significant 3D similarities to the human (h) 11βHSD1 and 2 structures. The contact energy profiles of the m11βHSD2 model were...

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Bibliographic Details
Main Authors: Yamaguchi, Hideaki, Akitaya, Tatsuo, Kidachi, Yumi, Kamiie, Katsuyoshi, Noshita, Toshiro, Umetsu, Hironori, Ryoyama, Kazuo
Format: Online
Language:English
Published: Libertas Academica 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236009/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236009/

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