Furin-cleaved Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Is Active and Modulates Low Density Lipoprotein Receptor and Serum Cholesterol Levels

Background: Two forms of PCSK9, an intact and a furin cleaved form, circulate in blood.

Bibliographic Details
Main Authors: Lipari, Michael T., Li, Wei, Moran, Paul, Kong-Beltran, Monica, Sai, Tao, Lai, Joyce, Lin, S. Jack, Kolumam, Ganesh, Zavala-Solorio, Jose, Izrael-Tomasevic, Anita, Arnott, David, Wang, Jianyong, Peterson, Andrew S., Kirchhofer, Daniel
Format: Online
Language:English
Published: American Society for Biochemistry and Molecular Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527935/