Robust tumor immunity to melanoma mediated by interleukin 9

Robust tumor immunity to melanoma mediated by interleukin 9

Interleukin-9 is a T cell cytokine that acts through a γC-family receptor on target cells. We determined that T cells from mice deficient in the TH17 pathway genes ROR-γ and IL-23R produced abundant IL-9, and observed significant growth inhibition of B16F10 melanoma tumor in these mice. IL-9 blockin...

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Bibliographic Details
Main Authors: Purwar, Rahul, Schlapbach, Christoph, Xiao, Sheng, Kang, Hong Soon, Elyaman, Wassim, Jiang, Xiaodong, Jetten, Anton M, Khoury, Samia J., Fuhlbrigge, Robert C, Kuchroo, Vijay K, Clark, Rachael A, Kupper, Thomas S
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518666/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518666/

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