Is There a Role for HTLV-1-Specific CTL in Adult T-Cell Leukemia/Lymphoma?
ATLL is an aggressive malignancy of T cells that affects about 5% of individuals infected with HTLV-1. The precise mechanism of oncogenesis is not known, but there is evidence that two regulatory viral proteins, Tax and HBZ, are involved. A high set point proviral load is associated with development...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Hindawi Publishing Corporation
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504207/ |