Unimpaired Skin Carcinogenesis in Desmoglein 3 Knockout Mice

The contribution of adherens junction inactivation, typically by downregulation or mutation of the transmembrane core component E-cadherin, to cancer progression is well recognized. In contrast, the role of the desmosomal cadherin components of the related cell-cell adhesion junction, the desmosome,...

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Bibliographic Details
Main Authors: Baron, Sylvain, Hoang, Anabel, Vogel, Hannes, Attardi, Laura D.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503716/