Desmoglein 2 Is Less Important than Desmoglein 3 for Keratinocyte Cohesion

Desmosomes provide intercellular adhesive strength required for integrity of epithelial and some non-epithelial tissues. Within the epidermis, the cadherin-type adhesion molecules desmoglein (Dsg) 1–4 and desmocollin (Dsc) 1–3 build the adhesive core of desmosomes. In keratinocytes, several isoforms...

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Bibliographic Details
Main Authors: Hartlieb, Eva, Kempf, Bettina, Partilla, Miriam, Vigh, Balázs, Spindler, Volker, Waschke, Jens
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543261/