Multifactor dimensionality reduction: An analysis strategy for modelling and detecting gene - gene interactions in human genetics and pharmacogenomics studies
The detection of gene - gene and gene - environment interactions associated with complex human disease or pharmacogenomic endpoints is a difficult challenge for human geneticists. Unlike rare, Mendelian diseases that are associated with a single gene, most common diseases are caused by the non-linea...
Main Authors: | Motsinger, Alison A, Ritchie, Marylyn D |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2006
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500181/ |
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