A Simple and Computationally Efficient Approach to Multifactor Dimensionality Reduction Analysis of Gene-Gene Interactions for Quantitative Traits

A Simple and Computationally Efficient Approach to Multifactor Dimensionality Reduction Analysis of Gene-Gene Interactions for Quantitative Traits

We present an extension of the two-class multifactor dimensionality reduction (MDR) algorithm that enables detection and characterization of epistatic SNP-SNP interactions in the context of a quantitative trait. The proposed Quantitative MDR (QMDR) method handles continuous data by modifying MDR’s c...

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Bibliographic Details
Main Authors: Gui, Jiang, Moore, Jason H., Williams, Scott M., Andrews, Peter, Hillege, Hans L., van der Harst, Pim, Navis, Gerjan, Van Gilst, Wiek H., Asselbergs, Folkert W., Gilbert-Diamond, Diane
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689797/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689797/

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