Use of Four Next-Generation Sequencing Platforms to Determine HIV-1 Coreceptor Tropism

Use of Four Next-Generation Sequencing Platforms to Determine HIV-1 Coreceptor Tropism

HIV-1 coreceptor tropism assays are required to rule out the presence of CXCR4-tropic (non-R5) viruses prior treatment with CCR5 antagonists. Phenotypic (e.g., Trofile™, Monogram Biosciences) and genotypic (e.g., population sequencing linked to bioinformatic algorithms) assays are the most widely us...

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Bibliographic Details
Main Authors: Archer, John, Weber, Jan, Henry, Kenneth, Winner, Dane, Gibson, Richard, Lee, Lawrence, Paxinos, Ellen, Arts, Eric J., Robertson, David L., Mimms, Larry, Quiñones-Mateu, Miguel E.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498215/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498215/

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