Systematic Identification of Synergistic Drug Pairs Targeting HIV

The systematic identification of effective drug combinations has been hindered by the unavailability of methods that can explore the large combinatorial search space of drug interactions. Here we present a multiplex screening method named MuSIC (Multiplex Screening for Interacting Compounds), which...

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Bibliographic Details
Main Authors: Tan, Xu, Hu, Long, Luquette, Lovelace J., Gao, Geng, Liu, Yifang, Qu, Hongjing, Xi, Ruibin, Lu, Zhi John, Park, Peter J., Elledge, Stephen J.
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494743/