Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells
PARP inhibitors have been proposed as a potential targeted therapy for patients with triple-negative (ER-, PR-, HER2-negative) breast cancers. However, it is as yet unclear as to whether single agent or combination therapy using PARP inhibitors would be most beneficial. To better understand the mech...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
WILEY-VCH Verlag
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491838/ |