Towards a new tuberculosis drug: pyridomycin – nature's isoniazid
Tuberculosis, a global threat to public health, is becoming untreatable due to widespread drug resistance to frontline drugs such as the InhA-inhibitor isoniazid. Historically, by inhibiting highly vulnerable targets, natural products have been an important source of antibiotics including potent ant...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
WILEY-VCH Verlag
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491834/ |