In vivo Genome Editing Using High Efficiency TALENs

In vivo Genome Editing Using High Efficiency TALENs

The zebrafish (Danio rerio) is increasingly being used to study basic vertebrate biology and human disease using a rich array of in vivo genetic and molecular tools. However, the inability to readily modify the genome in a targeted fashion has been a bottleneck in the field. Here we show that improv...

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Bibliographic Details
Main Authors: Bedell, Victoria M., Wang, Ying, Campbell, Jarryd M., Poshusta, Tanya L., Starker, Colby G., Krug, Randall G., Tan, Wenfang, Penheiter, Sumedha G., Ma, Alvin C., Leung, Anskar Y.H., Fahrenkrug, Scott C., Carlson, Daniel F., Voytas, Daniel F., Clark, Karl J., Essner, Jeffrey J., Ekker, Stephen C.
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491146/

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