Mannose-Binding Lectin Regulates Host Resistance and Pathology during Experimental Infection with Trypanosoma cruzi

Mannose-binding lectin (MBL) is a humoral pattern-recognition molecule important for host defense. Although recent genetic studies suggest an involvement of MBL/MASP2-associated pathways in Chagas’ disease, it is currently unknown whether MBL plays a role in host resistance to the intracellular prot...

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Bibliographic Details
Main Authors: Rothfuchs, Antonio Gigliotti, Roffê, Ester, Gibson, Amanda, Cheever, Allen W., Ezekowitz, R. Alan B., Takahashi, Kazue, Steindel, Mario, Sher, Alan, Báfica, André
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490958/