Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome

Innate immunity is the first-line defense against pathogens and relies on phagocytes, soluble components, and cell-surface and cytosolic pattern recognition receptors. Despite using hard-wired receptors and signaling pathways, the innate immune response demonstrates surprising specificity to differe...

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Bibliographic Details
Main Authors: Ip, W.K. Eddie, Takahashi, Kazue, Moore, Kathryn J., Stuart, Lynda M., Ezekowitz, R. Alan B.
Format: Online
Language:English
Published: The Rockefeller University Press 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234382/