The early antitumor immune response is necessary for tumor growth: Re-visiting Prehn’s hypothesis in the human melanoma system

Early events responsible of tumor growth in patients with a normal immune system are poorly understood. Here, we discuss, in the context of human melanoma, the Prehn hypothesis according to which a weak antitumor immune response may be required for tumor growth before weakly or non-immunogenic tumo...

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Bibliographic Details
Main Authors: Parmiani, Giorgio, Maccalli, Cristina
Format: Online
Language:English
Published: Landes Bioscience 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489749/