A senescent cell bystander effect: senescence-induced senescence
Senescent cells produce and secrete various bioactive molecules including interleukins, growth factors, matrix-degrading enzymes and reactive oxygen species (ROS). Thus, it has been proposed that senescent cells can damage their local environment, and a stimulatory effect on tumour cell growth and i...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Blackwell Publishing Ltd
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488292/ |