From promoting to inhibiting: diverse roles of helicases in HIV-1 Replication

Helicases hydrolyze nucleotide triphosphates (NTPs) and use the energy to modify the structures of nucleic acids. They are key players in every cellular process involving RNA or DNA. Human immunodeficiency virus type 1 (HIV-1) does not encode a helicase, thus it has to exploit cellular helicases in...

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Bibliographic Details
Main Authors: Lorgeoux, Rene-Pierre, Guo, Fei, Liang, Chen
Format: Online
Language:English
Published: BioMed Central 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484045/