Discovery of small molecule cancer drugs: Successes, challenges and opportunities

The discovery and development of small molecule cancer drugs has been revolutionised over the last decade. Most notably, we have moved from a one‐size‐fits‐all approach that emphasized cytotoxic chemotherapy to a personalised medicine strategy that focuses on the discovery and development of molecul...

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Bibliographic Details
Main Authors: Hoelder, Swen, Clarke, Paul A., Workman, Paul
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476506/