Small Molecule Drug Discovery at the Glucagon-Like Peptide-1 Receptor

The therapeutic success of peptide glucagon-like peptide-1 (GLP-1) receptor agonists for the treatment of type 2 diabetes mellitus has inspired discovery efforts aimed at developing orally available small molecule GLP-1 receptor agonists. Although the GLP-1 receptor is a member of the structurally c...

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Bibliographic Details
Main Authors: Willard, Francis S., Bueno, Ana B., Sloop, Kyle W.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352573/