Interaction between GSTP1 Val Allele and H. pylori Infection, Smoking and Alcohol Consumption and Risk of Gastric Cancer among the Chinese Population

Glutathione S-transferase P1 (GSTP1) is a critical enzyme in the phase II detoxification pathway. One of the common functional polymorphisms of GSTP1 is A→G at nucleotide 313, which results in an amino acid substitution (Ile105Val) at the substrate binding site and reduced catalytic activity. We eva...

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Bibliographic Details
Main Authors: Zhang, Ye, Sun, Li-Ping, Xing, Cheng-Zhong, Xu, Qian, He, Cai-Yun, Li, Ping, Gong, Yue-Hua, Liu, Yun-Peng, Yuan, Yuan
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471930/