The GSTP1 105Val Allele Increases Breast Cancer Risk and Aggressiveness but Enhances Response to Cyclophosphamide Chemotherapy in North China

The glutathione-S-transferase (GST) family contributes to the inactivation of various toxic compounds formed as secondary metabolites during oxidative stress. GSTP1 accounts for the majority of the GST family enzymatic activity, and the activity of GSTP1 enzyme can be altered by the presence of the...

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Bibliographic Details
Main Authors: Ge, Jie, Tian, Ai-Xian, Wang, Qing-Shan, Kong, Peng-Zhou, Yu, Yue, Li, Xiao-Qing, Cao, Xu-Chen, Feng, Yu-Mei
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691318/