Interleukin-33 Primes Mast Cells for Activation by IgG Immune Complexes

Mast cells (MCs) are heterogeneous cells whose phenotype is modulated by signals received from the local microenvironment. Recent studies have identified the mesenchymal-derived cytokine IL-33 as a potent direct activator of MCs, as well as regulator of their effector phenotype, and have implicated...

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Bibliographic Details
Main Authors: Kaieda, Shinjiro, Wang, Jun-Xia, Shnayder, Ruslan, Fishgal, Nadia, Hei, Hillary, Lee, Richard T., Stevens, Richard L., Nigrovic, Peter A.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469528/