Mitochondrial dysfunction and activation of iNOS are responsible for the palmitate-induced decrease in adiponectin synthesis in 3T3L1 adipocytes

Mitochondrial dysfunction and activation of iNOS are responsible for the palmitate-induced decrease in adiponectin synthesis in 3T3L1 adipocytes

Mitochondrial dysfunction and endoplasmic reticulum (ER) stress are considered the key determinants of insulin resistance. Impaired mitochondrial function in obese animals was shown to induce the ER stress response, resulting in reduced adiponectin synthesis in adipocytes. The expression of inducibl...

Full description

Bibliographic Details
Main Authors: Jeon, Min Jae, Leem, Jaechan, Ko, Myoung Seok, Jang, Jung Eun, Park, Hye-Sun, Kim, Hyun Sik, Kim, Mina, Kim, Eun Hee, Yoo, Hyun Ju, Lee, Chul-Ho, Park, In-Sun, Lee, Ki-Up, Koh, Eun Hee
Format: Online
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465750/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465750/

Similar Items