Interaction between Mitochondria and the Endoplasmic Reticulum: Implications for the Pathogenesis of Type 2 Diabetes Mellitus
Mitochondrial dysfunction and endoplasmic reticulum (ER) stress are closely associated with β-cell dysfunction and peripheral insulin resistance. Thus, each of these factors contributes to the development of type 2 diabetes mellitus (DM). The accumulated evidence reveals structural and functional co...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140192/ |