The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling

The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling

During developmental and tumor angiogenesis, semaphorins regulate blood vessel navigation by signaling through plexin receptors that inhibit the R-Ras subfamily of small GTPases. R-Ras is mainly expressed in vascular cells, where it induces adhesion to the extracellular matrix (ECM) through unknown...

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Bibliographic Details
Main Authors: Sandri, Chiara, Caccavari, Francesca, Valdembri, Donatella, Camillo, Chiara, Veltel, Stefan, Santambrogio, Martina, Lanzetti, Letizia, Bussolino, Federico, Ivaska, Johanna, Serini, Guido
Format: Online
Language:English
Published: Nature Publishing Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463263/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463263/

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