Sequential Actions of Rab5 and Rab7 Regulate Endocytosis in the Xenopus Oocyte

To explore the role of GTPases in endocytosis, we developed an assay using Xenopus oocytes injected with recombinant proteins to follow the uptake of the fluid phase marker HRP. HRP uptake was inhibited in cells injected with GTPĪ³S or incubated with aluminum fluoride, suggesting a general role for G...

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Bibliographic Details
Main Authors: Mukhopadhyay, Amitabha, Barbieri, Alejandro M., Funato, Kouichi, Roberts, Richard, Stahl, Philip D.
Format: Online
Language:English
Published: The Rockefeller University Press 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132516/