Superantigenic Activity of emm3 Streptococcus pyogenes Is Abrogated by a Conserved, Naturally Occurring smeZ Mutation

Superantigenic Activity of emm3 Streptococcus pyogenes Is Abrogated by a Conserved, Naturally Occurring smeZ Mutation

Streptococcus pyogenes M/emm3 strains have been epidemiologically linked with enhanced infection severity and risk of streptococcal toxic shock syndrome (STSS), a syndrome triggered by superantigenic stimulation of T cells. Comparison of S. pyogenes strains causing STSS demonstrated that emm3 strai...

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Bibliographic Details
Main Authors: Turner, Claire E., Sommerlad, Mary, McGregor, Karen, Davies, Frances J., Pichon, Bruno, Chong, Deborah L. W., Farzaneh, Leili, Holden, Matthew T. G., Spratt, Brian G., Efstratiou, Androulla, Sriskandan, Shiranee
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462185/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462185/

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