Microvesicles released from hormone-refractory prostate cancer cells facilitate mouse pre-osteoblast differentiation

Bone metastasis is often occurs in patients with prostate cancer. There is a vicious cycle for bone metastases involving prostate cancer cells, osteoblasts, and osteoclasts. Acting among those cells during the process of metastasis are several molecules such as bone morphogenetic proteins, platelet-...

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Bibliographic Details
Main Authors: Itoh, Tomohiro, Ito, Yuko, Ohtsuki, Yoshinori, Ando, Masashi, Tsukamasa, Yasuyuki, Yamada, Nami, Naoe, Tomoki, Akao, Yukihiro
Format: Online
Language:English
Published: Springer Netherlands 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460166/