Ube2W conjugates ubiquitin to α-amino groups of protein N-termini

The covalent attachment of the protein ubiquitin to intracellular proteins by a process known as ubiquitylation regulates almost all major cellular systems, predominantly by regulating protein turnover. Ubiquitylation requires the co-ordinated action of three enzymes termed E1, E2 and E3, and typica...

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Bibliographic Details
Main Authors: Tatham, Michael H., Plechanovová, Anna, Jaffray, Ellis G., Salmen, Helena, Hay, Ronald T.
Format: Online
Language:English
Published: Portland Press Ltd. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778709/