Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors
A combination of only five genes—BCL6, T, c-MYC, MITF, and BAF60C—rapidly and efficiently converts postnatal human amnion into chondrocytes. This direct conversion system from noncartilage tissue to cartilaginous tissue is a major advance toward understanding cartilage development, cell-based therap...
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| Format: | Online |
| Language: | English |
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The American Society for Cell Biology
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442400/ |
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pubmed-3442400 |
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pubmed-34424002012-11-30 Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors Ishii, Ryuga Kami, Daisuke Toyoda, Masashi Makino, Hatsune Gojo, Satoshi Ishii, Toshiharu Umezawa, Akihiro Articles A combination of only five genes—BCL6, T, c-MYC, MITF, and BAF60C—rapidly and efficiently converts postnatal human amnion into chondrocytes. This direct conversion system from noncartilage tissue to cartilaginous tissue is a major advance toward understanding cartilage development, cell-based therapy, and oncogenesis of chondrocytes. The American Society for Cell Biology 2012-09-15 /pmc/articles/PMC3442400/ /pubmed/22833560 http://dx.doi.org/10.1091/mbc.E11-10-0869 Text en © 2012 Ishii et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0). “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society of Cell BD; are registered trademarks of The American Society of Cell Biology. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Ishii, Ryuga Kami, Daisuke Toyoda, Masashi Makino, Hatsune Gojo, Satoshi Ishii, Toshiharu Umezawa, Akihiro |
| spellingShingle |
Ishii, Ryuga Kami, Daisuke Toyoda, Masashi Makino, Hatsune Gojo, Satoshi Ishii, Toshiharu Umezawa, Akihiro Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors |
| author_facet |
Ishii, Ryuga Kami, Daisuke Toyoda, Masashi Makino, Hatsune Gojo, Satoshi Ishii, Toshiharu Umezawa, Akihiro |
| author_sort |
Ishii, Ryuga |
| title |
Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors |
| title_short |
Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors |
| title_full |
Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors |
| title_fullStr |
Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors |
| title_full_unstemmed |
Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors |
| title_sort |
placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors |
| description |
A combination of only five genes—BCL6, T, c-MYC, MITF, and BAF60C—rapidly and efficiently converts postnatal human amnion into chondrocytes. This direct conversion system from noncartilage tissue to cartilaginous tissue is a major advance toward understanding cartilage development, cell-based therapy, and oncogenesis of chondrocytes. |
| publisher |
The American Society for Cell Biology |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442400/ |
| _version_ |
1611908893599858688 |