Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors
A combination of only five genes—BCL6, T, c-MYC, MITF, and BAF60C—rapidly and efficiently converts postnatal human amnion into chondrocytes. This direct conversion system from noncartilage tissue to cartilaginous tissue is a major advance toward understanding cartilage development, cell-based therap...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The American Society for Cell Biology
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442400/ |