Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors

A combination of only five genes—BCL6, T, c-MYC, MITF, and BAF60C—rapidly and efficiently converts postnatal human amnion into chondrocytes. This direct conversion system from noncartilage tissue to cartilaginous tissue is a major advance toward understanding cartilage development, cell-based therap...

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Bibliographic Details
Main Authors: Ishii, Ryuga, Kami, Daisuke, Toyoda, Masashi, Makino, Hatsune, Gojo, Satoshi, Ishii, Toshiharu, Umezawa, Akihiro
Format: Online
Language:English
Published: The American Society for Cell Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442400/