Myelin-Derived Lipids Modulate Macrophage Activity by Liver X Receptor Activation
Multiple sclerosis is a chronic, inflammatory, demyelinating disease of the central nervous system in which macrophages and microglia play a central role. Foamy macrophages and microglia, containing degenerated myelin, are abundantly found in active multiple sclerosis lesions. Recent studies have de...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440367/ |