Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles

The siRNA transfection efficiency of nanoparticles (NPs), composed of a superparamagnetic iron oxide core modified with polycationic polymers (poly(hexamethylene biguanide) or branched polyethyleneimine), were studied in CHO-K1 and HeLa cell lines. Both NPs demonstrated to be good siRNA transfection...

Full description

Bibliographic Details
Main Authors: Castillo, Betzaida, Bromberg, Lev, López, Xaira, Badillo, Valerie, González Feliciano, Jose A., González, Carlos I., Hatton, T. Alan, Barletta, Gabriel
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437298/