Development and characterization of chitosan-PEG-TAT nanoparticles for the intracellular delivery of siRNA

Recently, cell-penetrating peptides have been proposed to translocate antibodies, proteins, and other molecules in targeted drug delivery. The proposed study presents the synthesis and characterization of a peptide-based chitosan nanoparticle for small interfering RNA (siRNA) delivery, in-vitro. Spe...

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Bibliographic Details
Main Authors: Malhotra, Meenakshi, Tomaro-Duchesneau, Catherine, Saha, Shyamali, Kahouli, Imen, Prakash, Satya
Format: Online
Language:English
Published: Dove Medical Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666663/